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Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases

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Contributed by:Robert Hastings
Originally posted:3rd July 2009: 11:48 am
Last updated:3rd July 2009: 1:09 pm
Short URL:http://gen2phen.org/node/2386
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http://dx.doi.org/10.1093/aje/kwp119

A nice paper on current experiences and challanges of GWAS data.summarised from the paper abstract below"Genome-wide association studies (GWAS) have led to a rapid increase in available data on common genetic variants and phenotypes and numerous discoveries of new loci associated with susceptibility to common complex diseases. Integrating the evidence from GWAS and candidate gene studies depends on concerted efforts in data production, online publication, database development, and continuously updated data synthesis. Here the authors summarize current experience and challenges on these fronts, which were discussed at a 2008 multidisciplinary workshop sponsored by the Human Genome Epidemiology Network."

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