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Cancer GAMAdb: database of cancer genetic associations from meta-analyses and genome-wide association studies

Contributed by:Administrator
Originally posted:19th April 2011: 2:29 pm
Last updated:21st July 2011: 9:00 am
Short URL:http://gen2phen.org/node/37949
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2011.53
URL: 
http://dx.doi.org/10.1038/ejhg.2011.53

Abstract:

Gene set analysis of SNP data: benefits, challenges, and future directions

Contributed by:Administrator
Originally posted:13th April 2011: 12:00 am
Last updated:21st July 2011: 9:00 am
Short URL:http://gen2phen.org/node/37952
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2011.57
URL: 
http://dx.doi.org/10.1038/ejhg.2011.57

Gene set analysis of SNP data: benefits, challenges, and future directions

European Journal of Human Genetics advance online publication, April 13, 2011. doi:10.1038/ejhg.2011.57

Authors: Brooke L Fridley & Joanna M Biernacka

Abstract


Variable set enrichment analysis in genome-wide association studies

Contributed by:Administrator
Originally posted:25th March 2011: 10:25 am
Last updated:21st July 2011: 9:00 am
Short URL:http://gen2phen.org/node/36822
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2011.46
URL: 
http://dx.doi.org/10.1038/ejhg.2011.46

Abstract

NordicDB: a Nordic pool and portal for genome-wide control data

Contributed by:Administrator
Originally posted:29th July 2010: 12:09 pm
Last updated:18th November 2010: 10:30 am
Short URL:http://gen2phen.org/node/24962
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2010.112
URL: 
http://dx.doi.org/10.1038/ejhg.2010.112

Abstract:

Genome-wide gene and pathway analysis

Contributed by:Administrator
Originally posted:7th May 2010: 12:45 pm
Last updated:19th August 2010: 1:31 pm
Short URL:http://gen2phen.org/node/21289
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2010.62
URL: 
http://dx.doi.org/10.1038/ejhg.2010.62

Genome-wide gene and pathway analysis

European Journal of Human Genetics advance online publication, May 5, 2010. doi:10.1038/ejhg.2010.62

Authors: Li Luo, Gang Peng, Yun Zhu, Hua Dong, Christopher I Amos & Momiao Xiong

Abstract:

Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies

Contributed by:Administrator
Originally posted:17th March 2010: 1:00 am
Last updated:17th June 2010: 8:00 am
Short URL:http://gen2phen.org/node/14429
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2010.26
URL: 
http://dx.doi.org/10.1038/ejhg.2010.26

European Journal of Human Genetics advance online publication, March 17, 2010. doi:10.1038/ejhg.2010.26

Authors: Konstantinos C M Siontis, Nikolaos A Patsopoulos & John P A Ioannidis

Abstract

Italian appeal court: a genetic predisposition to commit murder?

Contributed by:Administrator
Originally posted:16th March 2010: 11:24 am
Last updated:22nd April 2010: 9:00 am
Short URL:http://gen2phen.org/node/14164
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2010.31
URL: 
http://dx.doi.org/10.1038/ejhg.2010.31

Italian appeal court: a genetic predisposition to commit murder?

European Journal of Human Genetics advance online publication, March 10, 2010. doi:10.1038/ejhg.2010.31

Authors: Francesca Forzano, Pascal Borry, Anne Cambon-Thomsen, Shirley V Hodgson, Aad Tibben, Petrus de Vries, Carla van El & Martina Cornel

Abstract:

Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power

Contributed by:Administrator
Originally posted:23rd July 2009: 11:05 am
Last updated:23rd July 2009: 11:06 am
Short URL:http://gen2phen.org/node/3000
Public document Public - anyone can view
DOI: 
10.1038/ejhg.2009.7
URL: 
http://dx.doi.org/10.1038/ejhg.2009.7

Recent developments in genome-wide association studies (GWAS) have lead to the localization of disease genes for many complex diseases. The scrutiny of the respective publications reveals, first, that statistical analysis is restricted typically to single-marker analysis in the first step, and that, second, the presence of multiple, independently associated SNPs within the same linkage disequilibrium (LD) region is a common phenomenon.

Personal genomics services: whose genomes?

Contributed by:Administrator
Originally posted:18th June 2009: 12:00 am
Last updated:23rd July 2009: 11:53 am
Short URL:http://gen2phen.org/node/2769
Public document Public - anyone can view
URL: 
http://dx.doi.org/10.1038/ejhg.2008.254

New companies offering personal whole-genome information services over the internet are dynamic and highly visible players in the personal genomics field. For fees currently ranging from US$399 to US$2500 and a vial of saliva, individuals can now purchase online access to their individual genetic information regarding susceptibility to a range of chronic diseases and phenotypic traits based on a genome-wide SNP scan. Most of the companies offering such services are based in the United States, but their clients may come from nearly anywhere in the world.

G2P Knowledge Centre is part of GEN2PHEN and funded by the Health Thematic Area of the Cooperation Programme of the European Commission within the VII Framework Programme for Research and Technological Development.

© GEN2PHEN 2011