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High marks for GWAS

Contributed by:Administrator
Originally posted:30th June 2009: 4:04 pm
Last updated:30th June 2009: 4:32 pm
Short URL:http://gen2phen.org/node/2280
Public document Public - anyone can view
DOI: 
10.1038/ng0709-765
URL: 
http://www.nature.com/ng/journal/v41/n7/full/ng0709-765.html

Two genome-wide association studies for testicular cancer report associations at three new loci, including two candidate genes previously implicated in testicular development, KITLG (ligand for the receptor tyrosine kinase) and SPRY4 (sprouty 4). These studies are notable for the high effect sizes detected and the biological plausibility of the candidate genes.

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