Principles and challenges of genome-wide DNA methylation analysis

Posted Wed, 03/02/2010 - 10:56
DOI: 
10.1038/nrg2732
URL: 
http://feeds.nature.com/~r/nrg/rss/aop/~3/lJ17UWvFWTg/nrg2732

Mapping DNA methylation is vital for understanding the importance of this epigenetic mark in health and disease. Recent years have seen rapid progress in the development of techniques for genome-scale methylation profiling; this Review introduces and evaluates the available methods.

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