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Infectious diseases not immune to genome-wide association

Contributed by:Administrator
Originally posted:27th August 2010: 11:00 am
Last updated:31st August 2010: 9:01 am
Short URL:http://gen2phen.org/node/26422
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DOI: 
10.1038/ng0910-731
URL: 
http://feeds.nature.com/~r/ng/rss/current/~3/gQ5spYUUZJU/ng0910-731

Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations.

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