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A framework for variation discovery and genotyping using next-generation DNA sequencing data

Contributed by:Administrator
Originally posted:19th April 2011: 2:06 pm
Short URL:http://gen2phen.org/node/38215
Public document Public - anyone can view
DOI: 
10.1038/ng.806
URL: 
http://feeds.nature.com/~r/ng/rss/aop/~3/1GRrDf_GPbM/ng.806

Mark DePristo and colleagues report an analytical framework to discover and genotype variation using whole exome and genome resequencing data from next-generation sequencing technologies. They apply these methods to low-pass population sequencing data from the 1000 Genomes Project.

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