Genotype imputation is an important tool for genome-wide association studies as it
increases power, aids in fine-mapping of associations and facilitates meta-analyses. This
Review provides a guide to and comparison of imputation methods and discusses association
testing using imputed data.
G2P Knowledge Centre is part of GEN2PHEN and funded by the Health Thematic Area of the Cooperation Programme of the European Commission
within the VII Framework Programme for Research and Technological Development.